Crosslinking, Labeling and Protein Modification
Sigma Aldrich Fine Chemicals Biosciences Phalloidin Atto 390 suitab
Atto 390 Phalloidin is a novel fluorescent label with a coumarin structure. The dye is intended for application in the area of life science e.g. labeling of DNA RNA or proteins. Characteristic features of the label are high fluorescence quantum yield large Stokes-shift good photostability and low molecular weight.Phalloidin is a fungal toxin isolated from the poisonous mushroom Amanita phalloides. Its toxicity is attributed to the ability to bind f actin in liver and muscle cells. As a result of binding phalloidin actin filaments become strongly stabilized. Phalloidin has been found to bind only to polymeric and oligomeric forms of actin and not to monomeric actin. The dissociation constant of the actin-phalloidin complex has been determined to be on the order of 3 x 10-8. Phalloidin differs from amanitin in rapidity of action at high dose levels death of mice or rats occurs within 1 or 2 hours.
Sigma Aldrich Fine Chemicals Biosciences Atto 655 NHS ester BioReag1MG
ATTO Atto 655 NHS ester BioReag1MG
AG Scientific Inc Collagenase A Animal Free, 1 G
Collagenase derived from cultures grown in animal-free medium, Suitable for applications needing to avoid introduction of potential animal derived pathogens into bioprocessing procedures.Storage Temperature: +2-8CResearch or further manufacturing use only, not for food or drug use.
Medchemexpress LLC IL-17A Rat CHO 50ug | 50ug
The IL-17A protein has important heterodimerization and homodimerization activities and is involved in a variety of processes including responses to glucocorticoid stimulation and the regulation of cell death and transcription IL-17A is present in the cytoplasm and extracellular space and has been implicated in diseases such as pancreatitis inflammatory bowel disease renal disease and periodontal disease and may serve as a biomarker IL-17A Protein Rat (CHO) is the recombinant rat-derived IL-17A protein expressed by CHO with tag free
Medchemexpress LLC Tos-PEG4-acid | 1453117-42-4 | 97.2% | 25 MG
Tos-PEG4-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. These PROTACs consist of two ligands linked together, one for an E3 ubiquitin ligase and the other for a target protein, enabling the selective degradation of target proteins via the intracellular ubiquitin-proteasome system. It has a molecular weight of 376.42 and a chemical formula of C16H24O8S, presenting as a colorless to light yellow liquid.
- PEG-based PROTAC linker
- Facilitates synthesis of PROTACs
- Molecular weight of 376.42
- Chemical formula: C16H24O8S
- Appears as a colorless to light yellow liquid